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Relation Between Smoking and Risk of Dementia and Alzheimer Disease: The Rotterdam Study
Neurol 69:998-1005, Reitz,C.,et al, 2007
See this aricle in Pubmed

Article Abstract
Current smoking increases the risk of dementia. This effect is more pronounced in persons without the AOPE?4 allele than the APOE?4 carriers.
 
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